Also targeted therapies like TKIs depend on achieving threshold intratumoral levels simply because evidenced simply by pharmacokinetic and pharmacogenomics research [27,41,42]

Also targeted therapies like TKIs depend on achieving threshold intratumoral levels simply because evidenced simply by pharmacokinetic and pharmacogenomics research [27,41,42]. Considering that small-molecule anti-cancer therapies need a threshold of…

There are a variety of causes but the major ones are medication, especially tricyclic antidepressants and sympathomimetic drugs, head and neck irradiation, and auto-immune inflammatory diseases such as Sjogren’s syndrome, which targets exocrine glands in general[13]

There are a variety of causes but the major ones are medication, especially tricyclic antidepressants and sympathomimetic drugs, head and neck irradiation, and auto-immune inflammatory diseases such as Sjogren's syndrome,…

For example, blood pressure lowering agents such as the ACE inhibitors, developed originally to reduce the risk of vascular injury and myocardial infarction were found to reduce stroke incidence [5],[6]

For example, blood pressure lowering agents such as the ACE inhibitors, developed originally to reduce the risk of vascular injury and myocardial infarction were found to reduce stroke incidence [5],[6].…