premutation service providers over age 50 may develop fragile X-associated tremor/ataxia syndrome (FXTAS), a neurodegenerative disorder characterized by intention tremor, cerebellar gait ataxia, neuropathy, and cognitive deficits in executive function, attention, memory space, and visual-spatial control (Brega mRNA toxic gain-of-function is the pathogenic molecular mechanism of neurodegeneration in FXTAS (Hagerman, 2013; Jacquemont premutation

January 10, 2022Posted inLTA4 Hydrolase
premutation service providers over age 50 may develop fragile X-associated tremor/ataxia syndrome (FXTAS), a neurodegenerative disorder characterized by intention tremor, cerebellar gait ataxia, neuropathy, and cognitive deficits in executive function,…

2016

December 29, 2021Posted inLTA4 Hydrolase
2016. is focused on overcoming barriers to efficacy via rational combinations that overcome resistance to therapy. expanded T cells and chimeric antigen receptor T cells (CAR-T)). CHECKPOINT BLOCKADE Rationale Checkpoint…