Although cyclophosphamide and corticosteroids have effects on B-cells, the advent of B-cell directed therapies using specific antibodies against CD20, CD22, and against B-cell survival factors and cytokines (anti-BAFF, anti-BR3, TACI-Ig, anti-IL10, anti-IL6), or agents modulating B-cell receptor strength (LJP394, Epratide) provide different mechanisms of action, potential different efficacies and different adverse events

February 26, 2025Posted inGlutamate (Kainate) Receptors
Although cyclophosphamide and corticosteroids have effects on B-cells, the advent of B-cell directed therapies using specific antibodies against CD20, CD22, and against B-cell survival factors and cytokines (anti-BAFF, anti-BR3, TACI-Ig,…

Significantly, an assortment of two mAbs to HER2, pertuzumab and trastuzumab, in conjunction with chemotherapy, considerably prolonged progression-free survival of breast cancer patients whose tumors overexpress HER2 (8)

February 21, 2025Posted inAlpha2 Adrenergic Receptors
Significantly, an assortment of two mAbs to HER2, pertuzumab and trastuzumab, in conjunction with chemotherapy, considerably prolonged progression-free survival of breast cancer patients whose tumors overexpress HER2 (8). capability of…

Proteins array probing Serum examples were diluted 1:100 in proteins array blocking buffer (Maine Production, Sanford, Me personally) supplemented with lysate (GenScript, Piscataway, NJ) to your final focus of 10 mg/ml, and pre-incubated in room heat range (RT) for 30 min

February 19, 2025Posted inTachykinin, Non-Selective
Proteins array probing Serum examples were diluted 1:100 in proteins array blocking buffer (Maine Production, Sanford, Me personally) supplemented with lysate (GenScript, Piscataway, NJ) to your final focus of 10…